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Dx Deep/ Superficial Vein Thrombosis Treatment:

Deep Vein Thrombosis

The Merck Manual Home Edition
"Deep vein thrombosis is the formation of blood clots (thrombi) in the deep veins.
Blood clots may form in veins if the vein is injured, a disorder causes the blood to clot, or something slows the return of blood to the heart.
1. Blood clots may cause the leg or arm to swell.
2. A blood clot can break loose and travel to the lungs, which is called a pulmonary embolism.
3. Doppler ultrasonography and blood tests are used to detect deep vein thrombosis.
4. Anticoagulants are given to prevent pulmonary embolism.

Blood clots (thrombi) can occur in the deep veins, termed deep vein thrombosis (DVT), or in the superficial veins, termed superficial venous thrombosis. In cases where the superficial veins are inflamed but without clotting (or thrombosis), this is referred to as superficial phlebitis (see see Superficial Venous Thrombosis). Deep vein thrombosis occurs most often in the legs or pelvis but may also occasionally develop in the arms".

Three main factors can contribute to deep vein thrombosis: *Injury to the vein's lining *An increased tendency for blood to clot *Slowing of blood flow.

Medications Used in Treatment:
1. Anticoagulants: Coumadin®, Xarelto®, Lovenox®, Pradaxa®, jantoven, heparin, Arixtra®, Fragmin®
2. PAI-1 Inhibitors: Stanozolol and Metformin®
3. Heparin®: Heparin
4. Factor Xa Inhibitor: Arixtra®/ Foundaparinux
5. Anabolic Anti PAI-1 Combination: Stanozolol and Metformin

Suggested Links
*N.H.S. Choice

OBSERVATION and Consideration for an Alternative Therapy
While most physicians are well informed in the use of Heparin® or Levonox® in risk situations of deep thrombophlebitis (blood clots); and familiar with coumadin as a long-term preventative for clots that could cause stokes (CVA); very few have ever heard of stanzolol and metformin. For a more complete discussion of the scientific information about all these prescription medications, consult Dx Fibrinolysis as this combination may be better tolerated for some and even life-saving for others.

*[Editor] Treatment of Superficial Thrombophlebitis of the lower extremity may include NSAIDs (motrim, naproxen, ibuprofen) or low molecular weight heparin. The newest medication, foundaparinux is $800 for 10 syringes and is suggested to be used for 45 days ($5000.00). Nine trials of topical treatments, 3 surgical treatments and 8 oral studies were inconclusive due to small sample size, low quality and poor reporting questioning whether any treatment more than a NSAID or Low Molecular Weight Heparin (LMWH) is really needed.

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