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Dx A.L.S. Treatments: ( Dx ALS ) Read More...


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SUMMARY:
Riluzole 100 mg daily is reasonably safe and probably prolongs median survival by about two to three months in patients with Amyotrophic Lateral Sclerosis. Riluzole generic is inexpensive.

Amyotrophic Lateral Sclerosis: Lou Gehrig's Disease

The Merck Manual states "Amyotrophic lateral sclerosis (ALS) and other motor neuron diseases (MNDs) are characterized by steady, relentless, progressive degeneration of corticospinal tracts, anterior horn cells, bulbar motor nuclei, or a combination. Symptoms vary in severity and may include muscle weakness and atrophy, fasciculations, emotional lability, and respiratory muscle weakness. Diagnosis involves nerve conduction studies, electromyography, and exclusion of other disorders via MRI and laboratory tests. Treatment is supportive."

Medications Used in Treatment::
1. Benzothiazoles: Rilutek®.
2. NMDA Receptor Antagonists/ Antiarrhythmic Combinations: Nuedexta®.
[Note that dextromethorphan 20mg and 10mg quinidine sulfate can be purchased separately at 1/10 (one-tenth) this cost].

Suggested Links:
*Medscape

National Organizations:
*ALS Association

*[Editor]
As of June 2013, Rilutek® is available as generic riluzole at one-tenth the cost of the brand name medication.

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