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Dx Epilepsy Dx Seizure Treatments:

Seizure Disorder:

The Merck Manual Home Edition
"In seizure disorders, the brain's electrical activity is periodically disturbed, resulting in some degree of temporary brain dysfunction.

  Many people have unusual sensations just before a seizure starts. Some seizures cause uncontrollable shaking and loss of consciousness, but more often, people simply stop moving or become unaware of what is happening.
  Doctors suspect the diagnosis based on symptoms, but imaging of the brain, blood tests, and electroencephalography (to record the brain's electrical activity) are usually needed to identify the cause.

If needed, drugs can usually help prevent seizures.
  Normal brain function requires an orderly, organized, coordinated discharge of electrical impulses. Electrical impulses enable the brain to communicate with the spinal cord, nerves, and muscles as well as within itself. Seizures may result when the brain's electrical activity is disrupted.

There are two basic types of seizures:
*Epileptic: These seizures have no apparent cause (or trigger) and occur repeatedly. These seizures are called a seizure disorder or epilepsy.
*Non-epileptic: These seizures are triggered (provoked) by a disorder or another condition that irritates the brain. In children, a fever can trigger a nonepileptic seizure (called a febrile seizure—see see Febrile Seizures).

Certain mental disorders can cause symptoms that resemble seizures, called psychogenic nonepileptic seizures.

About 2% of adults have a seizure at some time during their life. Two thirds of these people never have another one. Seizure disorders commonly begin in early childhood or in late adulthood."

Medications Used in Treatment:
1. Anti-epileptics: Neurontin®/gabapentin, Lamictal® Lamictal®XR/lamotrigine, Topamax® Trokendi®XR/topiramate, Lyrica®/pregabalin, Keppra® Keppra®XR/levetiracetam, Depakote® Depakote®ER/divalproex, Depakene® Stavzor®/valproic acid, Dilantin® Phenytek®/phenytoin, Felbatol®/felbamate, Zarontin®/ethosuximide, Trileptal®/oxcarbazepine, Epitol® Tegretol® Tegretol®XR Carbatrol®ER/carbamazepine, Gabitril®/tiagabine, Oxtellar®XR/oxcarbazepine, Mysoline®/primidone, Zonegran®/zonisamide, Vimpat®/lacosamide, Sabril®/vigabatrin, Peganone®/ethotoin
2. Benzodiazepines: Klonopin®/clonazepam, Diastat Acudial®/diazepam gel, Tranxene®/clorazepate
3. Barbituates: Seconal®/secobarbital
4. Carbonic Anhydrase Inhibitors: acetazolamide
5. Potassium Channel Openers: Potiga®/ezogabine
6. Adrenocorticotropic Hormones: H.P. Acthar®/ACTH
7. Anti-estrogenic and Anabolic Hormones: Danazol®/danocrine

Testimonial: Terri began having seizures in her teens. The seizures continued on all the aforementioned seizure medications. The key factor for treatment was that the seizures occurred just before the onset of her menstrual cycle. The Editor treated her with Danazol® just as he does with women with symptomatic Premenstrual Syndrome. Afterwards, the neurologist was able to control the seizures with standard anti-epileptic medication. As of now, she has been seizure free for 4 years. Childbearing cannot occur on danazol as it interferes with ovulation Danazol and equally effective mixture of anabolic medications might affect a female fetus.

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