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Dx Amoeba Diseases Treatment:


Most studies confirm that "Tinidazole is more effective in reducing clinical failure compared with metronidazole and has fewer associated adverse events. Combination drug therapy is more effective in reducing parasitological failure compared with metronidazole alone." Both are inexpensive.

Amoeba Diseases

The Merck Manual Home Edition states:
"Amebiasis is an infection of the large intestine and sometimes the liver and other organs that is caused by the single-celled protozoan parasite Entamoeba histolytica, an ameba. Amebiasis may cause diarrhea, cramping abdominal pain, pain over the liver, and fever. [It can often be confused with traveler's diarrhea, initially]. The amebas may be spread from person to person or through food or water. People may have no symptoms or may have diarrhea, cramping abdominal pain, tenderness in the upper abdomen, and fever. Doctors base the diagnosis on analysis of a stool sample and, if needed, other tests, such as colonoscopy or ultrasonography. People are given a drug that kills the amebas, followed by a drug that kills the dormant form of the amoebas." [Complete recovery is typical].

Medications Used in Treatment:
1. Macrolide Antibiotics: Erythromycin
2. Nitroimidazole Antibiotics: Flagyl®/ metrodiazole, Tindamax®
3. Antimalarials: Aralen®/ chloroquine.
4. Antiprotozoals: paromomycin.

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