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Dx Anemia: Acute and Chronic Anemia: Information and Treatment: Read More...


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ANEMIA:

You ask "What is ANEMIA?
ANEMIA IS the lack of RED BLOOD CELLS that are needed to carry oxygen to your body cells. Ask, "How can I know?"
*MEASURE ANEMIA either as the total HEMOGLOBIN(gm/dl). The out-of-pocket cost is $10.00. Order laboratory tests

*SEVERITY CAN BE MILD (hemoglobin 10- 12 mg/ml), MODERATE(< 10) or SEVERE(< 7).
**CAUSE: There is a net loss of hemoglobin when there is
    1) too much blood loss or
    2) inadequate blood formation.
**NON-SURGICAL TREATMENTS are effective more than 95% of the time when the blood loss is not severe and acute: DO BOTH
   1): HORMONES to Reduce the blood loss usually occurring from menstruating women, and
   2): Increase the blood formation with both a) oral iron and with hormones.
   3)STANDARD:
     MAN-MADE HORMONES: Oral Contraception and progestins cost about $10/ month.
     BEST, most effective: Danazol 200mg/#60 capsules/ month ABOUT 4150/ MONTH.
     MOST EXPENSIVE: Mireva® IUD $800/ 5 years; luprolide acetate $3500/ 2 years.
     [EDITOR'S CHOICE]: Nandrolone 2000mg/10ml. 20 to 40mg injection weekly/ year.
   MOST PROMOTED by drug companies and journal articles: Mireva® IUD $800/ 5 years; luprolide acetate $3500/ 2 years.

WORST CASE SCENARIO:
   There is a uniformity of treatment in the United States with the use of Eyrthropoietin agents for the most severe cases on anemia, including those with Chronic Kidney Disease (CKD). However, numerous medical journal articles related that nandrolone can be used for the treatment of anaemia of CKD in this category of patients, [especially] in resource-limited countries". Nandrolone has been available in the U.S. since 1962; today it is available in limited distribution from compounding pharmacies since Watson stopped production in 2007.
20-100mg Nadrolone injections per week are one-tenth the cost of 10,000 units/ml of Epogen®; when nandrolone is used concurrently, it can "lower [by 50%] doses of EPO ... sufficient for an adequate hematopoietic response."

Anemia of Chronic Disease

The Merck Manual Home Edition
states:
" In anemia of chronic disease, some chronic disorder slows the production of red blood cells and sometimes decreases survival of red blood cells.

Chronic disease often leads to anemia, especially in older adults. Conditions such as infections, inflammation, and cancer suppress production of red blood cells in the bone marrow. Because the bone marrow is unable to use stored iron to create new red blood cells, this type of anemia is often called iron-reutilization anemia. [The ferritin levels are quite adequate, but the body does not make red cells].

If the disorder causing the anemia does not respond to treatment, erythropoietin or darbepoietin, drugs that stimulate the bone marrow to produce red blood cells, may be given. Taking additional iron or vitamins does not help. On the rare occasion that the anemia becomes severe, transfusions may help."

Medications Used in Treatment:
1. Folate Analogues: folic acid, leucovorin
2. Iron and Oral Supplements: Ferocon®, Ferralet® 90, multi-vitamin
3. Iron Intravenous: Injectafer®, Venofer®
4. Erythropoiesis-Stimulating Agents: Epogen®, Procrit®, Aranesp®
5. Anabolic Steroids nandrolone.

*[Editor]: It is common knowledge in Spain that the F.D.A. approved anabolic steroids, especially inexpensive nandrolone, will reduce concurrent use of Erythropoietin products such as Epogen® by more than 50%..

For more information, see the Video entitled New Managements of Anemia
 with special emphasis on hormonal management.

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