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Dx Major Depression Disorders Alternative Treatment:

Clinical Depression

The Merck Manual Home Edition states:
"The disorder depression is a feeling of sadness intense enough to interfere with functioning. It may follow a recent loss or other sad event but is out of proportion to that event and lasts beyond an appropriate length of time."

Alternative Medications Used in the Treatment:
1. Sam-e
2. Exercise
3. Pregnenolone, 5-HTP and DHEA
4. Transcranial Magnetic Stimulator
5. Supplements of Amino-acids, Omega-3, Oral and Intravenous
6. Lightbox
7. IV ketamine

[Editor] A number of natural vitamins, minerals and supplements are used internationally to treat depression/anxiety. The two that have raised the most interest are 5-HTP and SAM-e.
*SAM-e and 5-HTP: The Medline and Cochrane Databases were searched...Supplements predominantly used by patients with depression include S-adenosylmethionine (SAM-e), l-tryptophan and 5-hydroxytryptophan (5-HTP) and inositol".
*Pregnenolone, "in the brain, neurosteroids such as allopregnanolone and pregnenolone, acting as positive TSPO modulators of gamma-aminobutyric type A (GABA(A)) receptors, exert anxiolytic activity [block anxiety]... Unlike benzodiazepines (Bzs), which represent the most common anti-anxiety drugs administered around the world, selective TSPO ligands have shown anxiolytic effects in animal models without any of the side effects associated with Benzodiazipines. Therefore, ...[these]... may represent the future of therapeutic treatment of anxiety/[depression] disorders".
*Omega-3 eicosapentacenoic acid (EPA) weighed preparations should be the focus of studies with depressive mood disorders than docosahexaenoic acid-weighted preparations.

[Editor] Major medical university research studies have concluded that a Light Box and "light therapy had a specific antidepressant effect beyond its placebo effect, but it took at least 3 weeks for a significant effect to develop. The benefit of light over placebo was in producing more of the full remissions."

Suggested Links
*N.H.S. Choice

[Editor] Screening for Laboratory tests may offer evidence that simple hormones may be out of balance. With these laboratory tests in hand, discuss them with your health care professional.

*See Depression/ Anxiety- All Natural Products

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