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Dx Acromegaly Treatment:


The consensus is that pre-surgical treatment with either lanreotide (Somatuline® depot) or octreotide (Sandostatin®/ Sandostatin Depot®) resulted is a more significant cure rate those then that went directly to surgery. In long-term studies, results were equivalent... but Sandostatin® daily is one-tenth the cost.


The Merck Manual Home Edition
" Gigantism and acromegaly are syndromes of excessive secretion of growth hormone (hypersomatotropism) that are nearly always due to a pituitary adenoma. Before closure of the epiphyses, the result is gigantism. Later, the result is acromegaly, which causes distinctive facial and other features. Diagnosis is clinical and by skull and hand x-rays and measurement of growth hormone levels. Treatment involves removal or destruction of the responsible adenoma."

Medications Used in Treatment:
1. Ergot Derivatives: Parlodel®
2. Somatostatin Analogues: Sandostatin®, Sandostatin Lar® Depot,Somatuline® Depot
4. Growth Hormone Receptor Antagonists: Somavert®/ pegvisomant:

Suggested Links
*Acromegaly Support Organization

*[Editor]: Only Sandostatin is least expensive at this time.

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