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Dx Testosterone Levels Raised Naturally: Read more...


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Observation:
Raising Male Testosterone Naturally

Journal of International Society of Sports Nutrition
states:
"The purpose of this study was to determine the effects of 6-OXO, a purported nutritional aromatase inhibitor, in a dose dependent manner on body composition, serum hormone levels, and clinical safety markers in resistance trained males. Sixteen males were supplemented with either 300 mg or 600 mg of 6-OXO in a double-blind manner for eight weeks. Blood and urine samples were obtained at weeks 0, 1, 3, 8, and 11 (after a 3-week washout period). Blood samples were analyzed for total testosterone (TT), free testosterone (FT), dihydrotestosterone (DHT), estradiol, estriol, estrone, SHBG, leutinizing hormone (LH), follicle stimulating hormone (FSH), growth hormone (GH), cortisol, FT/estradiol (T/E). Blood and urine were also analyzed for clinical chemistry markers. Data were analyzed with two-way MANOVA. For all of the serum hormones, there were no significant differences between groups (p > 0.05). Compared to baseline, free testosterone underwent overall increases of 90% for 300 mg 6-OXO and 84% for 600 mg, respectively (p < 0.05). DHT underwent significant overall increases (p < 0.05) of 192% and 265% with 300 mg and 600 mg, respectively. T/E increased 53% and 67% for 300 mg and 600 mg 6-OXO, respectively. For estrone, 300 mg produced an overall increase of 22%, whereas 600 mg caused a 52% increase (p < 0.05). Body composition did not change with supplementation (p > 0.05) and clinical safety markers were not adversely affected with ingestion of either supplement dose (p > 0.05). While neither of the 6-OXO dosages appears to have any negative effects on clinical chemistry markers, supplementation at a daily dosage of 300 mg and 600 mg for eight weeks did not completely inhibit aromatase activity, yet significantly increased FT, DHT, and T/E."

*[Editor]
The Internet reports "The main component of 6-OXO is called 4-Etioallocholen-3,6,17-Trione. This is standard nomenclature for this chemical, but it is also known as 4-Androstene-3,6,17-trione. This chemical is what is known as an aromatase inhibitor. But what does any of this mean?

What is Aromatase?

Aromatase is an enzyme that converts androgens (namely testosterone) into estrogen. 4-Androstene-3,6,17-trione inhibits this enzyme and prevents the conversion of testosterone in to estrogen. By doing this, testosterone levels are raised (because less testosterone is broken down) and estrogen levels are lowered (because less extra testosterone is converted to estrogen). This is the reasons many steroid users turn to 6-OXO during and after cycles. Excess testosterone is normally converted to estrogen and leads to the telltale signs of steroid abuse (breast tissue formation, elevated body fat, etc). By using this compound, the excess testosterone is unable to be converted, and thus does not contribute to these side effects."


*[Editor]
PODCAST Focus On Healing the Body and Relationships with Natural Hormones

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